ICHG2011: Debating the future of genome sequencing is medicine

Yesterday night at the International Congress on Human Genetics we had a debate, entitled “Current and Emerging Sequencing Technologies: Changing the Practice of Medical Genetics”. You can see the full list of participants here.

The debate was pretty lively, and in parts both enlivening and depressing. Below are a few points that I found interesting.

As always, you can find more coverage of ICHG on twitter (@lukejostins for me, #ICHG2011 for aggregated coverage).

Different perspectives

Joris Veltman described his exome sequencing of 500 individuals with intractable disease, and noted that there has been much success, and very little evidence of harm. Ségolène Aymé mentioned NIH targts that hope to see almost all genetic diseases diagnosed by 2020, and new treatments for rare diseases to be developed simultaneously. There seemed to be a solid consensus across the panel that sequencing should be rolled out as a standard tool in the diagnosis of genetic diseases, provided that the approach is a targeted one, restricted to finding the pathogenic mutation(s) causing the disease.

More controversial was the role of sequencing of healthy individuals, and the general return of data to patients or doctors for any reason other than directly diagnosing a genetic disease. Rade Drmanac, chief scientific officer of Complete Genomics, was obviously strongly in favour of everyone having their genome sequenced, and made it clear that Complete Genomics intends to start offering sequencing to doctors in the future. In his vision, genomes are sequenced at birth, and an initial analysis of immediately actionable results (e.g. potential genetic diseases) is passed to the doctor and patient, with further analyses being carried out if and when they are required.

Michael Hayden immediately dismissed this as hype. He pointed out how unable the US is to handle medical sequencing, with no good systems of reimbursement, a massive shortage of genetic councilors, and a general lack of training in the medical profession.While more positive in general, Louanne Hudgins also expressed worries about the lack of knowledge of genetics among doctors, with some truly scary examples of MDs failing to understanding even the most basic genetics.

Squabbling versus consensus building

The debate was lively, and very interesting, but started to get frustrating as time went on, and more questions and comments came from the floor. At times it seemed like a consensus might be in sight, but there was also a whole morass of squabbling that seems to get in the way. Those who are strongly in favor of rolling out sequencing argue against the conservative elements that they see as throwing out obstructions in the form of unfounded worries, and just want to defend their paternalistic tendencies against the onslaught of patient freedom. Those who are against argue against the liberals on the grounds that they are hyping the tech, and haven’t properly considered the welfare of the patients.

However, neither side really seems to fundamentally disagree on the findings of fact. Getting informed consent is difficult, but not impossible, or at least not more impossible than for other medical tests. There need to be more genetic councilors, and better education of doctors, but this is increasingly happening, and good annotation software and communication of genetic results will help things along (and is also happening). Genome quality is still not perfect, we need to ensure things are validated, and the associated costs are still relatively high. There exists some actionable information in the genome (the amount grows every year), and in the right circumstances this could improve treatment and prevent disease, but the efficacy of this approach, and its cost effectiveness, will need to be carefully assessed.

I feel that the time for debate is drawing to a close. If we wanted to we could keep on fighting, accusing each other of being clueless scientists who have never treated a patient, or out-of-date clinicians scared of new technology, or sequencing company shills who are only interested in selling genomes. However, the age of the genome is arriving whether we like it or not as a larger number of companies are now offering genome sequence for commodity prices, and we need to start getting ready. Both Michael Hayden and Louanne Hudgins ended the session with a plea to the American Society of Human Genetics and related societies to start to set out standards for the use of genomes in medicine. Now is the time to be finding things to agree on, to compromise on those that we don’t, and forge a consensus on which the future of genomic medicine can be built.

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42 Responses to ICHG2011: Debating the future of genome sequencing is medicine

  1. from the rest of the world who could not attend: thanxx so much for the coverage.

  2. Hi Luke,

    Thanks for the updates – they’re much appreciated.

    I have to admit, I’m somewhat shocked by Dr. Hayden’s point in rebuttal to Dr. Drmanac’s “hype”, which seems to be that the U.S. isn’t ready for it, so it shouldn’t happen. First, I hope the argument was more nuanced than that. (I know how hard it can be to encapsulate someone’s argument when blogging!) Second, I find that reason to be entirely obtuse… there are many other big markets outside of the U.S. that HAVE figured out how to deliver health care to their citizens, even if it is a fine balancing act.

    RANT: Whether we like it or not, medicine moves forward when we find new diagnostic tools – and this one has the potential to provide good diagnostic tools. The fact that it also can provide more nuanced information that we have to learn to interpret is no reason to shy away from the technology as a whole. Doctors will learn how to use the information when it gives them a better tool for saving lives, and improving the quality of life for their patients. /RANT.

    At any rate, I hope the conference is going well, and I appreciate the bits of information you’re able to share! Thanks again!

  3. I, too, want to thank you for summarizing what took place at the meeting between the “conservatives” and “liberals.” It sounded like the halls of Congress with those that want to stick their heads in the sand (genomic analysis has no place in medicine) versus those who feel, like I do, that genomics is the medicine of the future. The bottom line is that insurance carriers, doctors and governing bodies need to get their act together. People as evidenced by “Occupy WallStreet” are no longer content to let the power elite dictate how to use information. Squabbling over turf or scientific partisanship does not improve the quality of life for patients.

  4. Thanks for the coverage!

    I am definitely a ‘liberal’ when it comes to sequencing, and the venues in which it should be applied. I think that the diagnostic benefits that can be obtained will revolutionize medicine.

    I would also agree that current US medicine is not ready for routine clinical sequencing. However, I think that the rate of development of genomics and genetics provides the US healthcare industry an opportunity to evolve over the next decade. Open more Genetic Counseling programs in order to train more counselors. Improve on genetic training of doctors. And take the opportunity to educate the general public.

    I see these challenges as opportunities, not insurmountable obstacles. There in lies hope for success.

    Keep up the great blog.

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  7. Marian Rateb

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  8. Sheila Taylor

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  11. How I Got My Ex Husband Back………..

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

  12. Is my gratitude and honor to say a big thanks to a man with truth and do as he promise please every one on this site should join me and thank Dr.voodoo for the glory and happiness he gave to me i break up with my husband 2 weeks back and I was down and do not know what to do until i saw a post about this spell caster Dr.voodoo who i explain my situation to,and them he said to me cry not my daughter for what you seek for is right here in my temple he gave me hope when i have no hope to my greatest notice,he did the spell for me and my husband was back 3 days after the spell please if you need any help my advise is for you all go to Dr.voodoo because he is the best of all contact him via; voodoospelltemple66@gmail.com

  13. I wake up everyday with a smile on my face and singing praises to this powerful spell caster called Dr,UZOYA who has done me a great favor by rescuing my relationship from break up. I used to think that i have a perfect relationship till when my lover started coming home late and everyday he gives me different excuses then i decided to keep a close eye on him then i discovers that he was having an affair with another girl. I was heart broken because i trusted him so much and knowing that he has a secret relationship, hurts me a lot.. But i thank all those who placed the contact information of Dr,UZOYA on the internet because through that i have been able to contact Dr,UZOYA and today my relationship has been restored with love and more romance than ever before. If you are in any kind of relationship or marriage stress i will do you a favor by dropping the contact information’s of Dr,UZOYA which are via email: driraborspellcaster@gmail.com Or Call +2348151098492.

  14. Billy Hill

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  15. orna Harron

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  16. I am Shannon

    How I Got My Ex Husband Back………..

    I am Shannon by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address Makospelltemple@yahoo.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.Mako. His email: Makospelltemple@yahoo.com OR. his phone number: +2348108737816.

  17. How can I explain this to the world that there is a man called Dr uzoya who helped me bring back my ex lover and restored my womb..when all hope was lost..Me and my lover have been married for the past 5 years with no child we were living happily..on till one day that we have an understanding because i had not be able to have a child for him, so he decided to live me because of another women, i was so sad and frustrated and i could not even eat on till one day i was browsing through the internet where i saw a lady called Jessica testifying about spell caster call Dr uzoya who helped her brought back her husband back home, so i decided to take a try in contacting the spell caster Dr uzoya so i explain all my problem to Dr uzoya and he told me that i should not worry that he is going to help me solve my problem,that my lover will come back home to my greatest surprise in just 24 hours my husband start calling me and begging for forgiveness i was so surprise now we are back again as husband and wife,all my thanks goes to DR,UZOYA, worry no more cause DR,UZOYA is here to help u all,i will do u favor my drooping his email; driraborspellcaster@gmail.com OR his telephone number is +2348151098492

  18. HELLO:
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  19. imelda Daher

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  20. I am Johan Lisa from Philippines, i am 31 years of old
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  21. Trust me i was lucky to have gotten these details greatogudugu@gmail.com online which belong to a powerful spell caster called Dr.Ogudugu, My relationship was not in good mood because in recent times i kept seeing myself having problems with my lover. Things eventually got out of hand when my lover opened up to me that she has decided to move on because she has some one else in her life and that was how my relationship was broken until i saw this powerful spell caster contact information on the internet and he was able to restore my relationship by getting my lover back to me.

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  23. james william

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    She called me pleading for my forgiveness for how she has treated me and that she loves me so much and will never cheat on me again and will marry me.And from that moment till now all we’ve been experiencing is happiness in our relationship.We’ll be getting married soon……..lol

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  24. I am so happy today because of what Dr,UZOYA did for me,my fiance broke up with me last three month because he thought i was cheating on him,so for the past three month now i have trying to plead with him but he still say the same thing that he does not want us to come back again that he can not trust me so i came in contact with Dr,UZOYA,who told me that my lover is going to come back to me if i work with him so i did what he ask me to do,after that he call me that within 48 hours that my lover is going to come back to me,can you believe that my lover is back to me ,he now love me more than before i am so happy, spell is good when you meet Dr,UZOYA if you need his help contact him [driraborspellcaster@gmail.com] or call +13019098775 call or email him and i promise that he is going to help you with any problem OK my name is BEARY JAREM i am from the United state of America

  25. I was very confuse when my husband that i married 11 years ago told me he needs a divorce simply because he fell in love with a lady she met in the bank, she took all her belongings and left my house even when i plead with him not to go but he insisted and left. It wasn’t easy at all for me because i was in pain and couldn’t go to work or even eat, i did many research on the internet when i came across some beautiful testimony people shared about Doctor UZOYA so i quickly contacted him and told him my story, I never knew Doctor UZOYA could be so nice, he told me that my husband will come back to me within 24 hours and every thing happened just as he said and then i concluded that i have found a God on Earth and i will continues to testify about him till Christ comes.u can contact him if u need any help: [driraborspellcaster@gmail.com] OR call him direct on +13019098775. thank u so much Dr,UZOYA

  26. My Husband divorce me for no reason, Thanks to Dr happy for bringing back my husband,and brought me great joy to my family once again, My name is crystal . i live in USA New Jersey, I`m happily married to a lovely and caring husband,with three kids A very big problem occurred in my family 2 weeks ago,between me and my husband so terrible that he took the case to court for a divorce he said that he never wanted to stay with me again,and that he did not love me anymore So he packed out of my house and made me and my children passed through several pain. I tried all my possible means to get him back,after much begging,but all to no avail and he confirmed it that he has made his decision,and he never wanted to see me again. So on one evening,as i was coming back from work,i met an old friend of mine who asked of my husband So i explained every thing to her,so she told me that the only way i can get my husband back,is to visit a spell caster,because it has really worked for her too So i never believed in spell,but i had no other choice,than to follow her advice. Then she gave me the email address of the spell caster whom she visited.(happylovespell2@gmail.com}, So the next morning,i sent a mail to the address she gave to me,and the spell caster assured me that i will get my husband back the next day what an amazing statement!! I never believed,so he spoke with me,and told me everything that i need to do. Then the next morning, So surprisingly, my husband who did not call me for the past seven {2}weeks,gave me a call to inform me that he was coming back So Amazing!! So that was how he came back that same day,with lots of love and joy,and he apologized for his mistake,and for the pain he caused me and my children. Then from that day,our relationship was now stronger than how it were before,by the help of a spell caster . So, i will advice you out there to kindly visit Dr happy ,if you are in any condition like this,or you have any problem related to “bringing your ex back. So thanks to Dr happy for bringing back my husband,and brought great joy to my family once again. { happylovespell2@gmail.com }, Thanks you Dr happy, i will always be testifying about your good work. also call him on +2348133873774.your spell is really a 100% Guarantee sure and safe

  27. Dr Ogudugu Spells

    I am Dr Ogudugu a Traditional healer, herbalist and spell caster. I use real magical powers to fight demons, evil spirits and super villains. Are you suffering in silence? does everything in your life seems to be going wrong no matter how hard you try to make things better? have Questions about love, or career let me help you am a born gifted traditional healer and master psychic. I ‘ve experience in exploration of the past, present and future. I can help you with any of those problems that are making your life difficult and miserable,do you have many enemies some enemies that you are not even aware of? are you having many obstacles in your life? Is your love,relationship,marriage life falling apart? is your life facing financial ruin ? i specialize in reuniting.Email me about your problems and i’ll be of great help to you on my personal email address: GREATOGUDUGU@GMAIL.COM

  28. I am here to share my testimony of how gracious i am to God I am being blessed through this wonderful man called Dr. Ogudugu. My life is back!!! After 3years of Broken marriage, my Wife left me with two kids. I felt like my life was about to end i almost committed suicide, i was emotionally down for a very long time. Thanks to a spell caster called Dr Ogudugu via: (greatogudugu@gmail.com),which i met online. On one faithful day, as I was browsing through the internet,i came across alot of testimonies about this particular spell caster. Some people testified that he brought their Ex lover back, some testified that he restores womb,cure cancer,and other sickness, some testified that he can cast a spell to stop divorce and so on. I also come across one particular testimony,it was about a woman called Ana,she testified about how he brought back her Ex lover in less than 2 days, and at the end of her testimony she dropped Dr Ogudugu e-mail address. After reading all these i decided to give it a try. I contacted him via email and explained my problem to him after doing all he ask me to do. In just 48hours, my Wife came back home to me and the kids. We solved our issues, and we are even happier than before Dr Ogudugu is really a gifted man and i will not stop publishing him because he is a wonderful man…If you have a problem and you are looking for a real and genuine spell caster to solve all your problems. Kindly contact High Dr Ogudugu via: greatogudugu@gmail.com anytime, he is the answer to your problems.

    HIV / AIDS

    HERPES / CANCER

    Need a divorce?

    You want your ex lover back?

    Do you want to get pregnant?

    You want to be famous or rich?

    Do you want super growth in your business

    You want to be good academically honorable?

    Need a job?

    You need a husband?

    Do you have a problem in your married life?

    Do you want to win the lottery or win a court case?

    I hope you find the solution and be happy as i am now ..So brothers and sisters i have tested this man Dr Ogudugu spell temple Trust and i have found that he is real and genuine. I am now the happiest Man on earth today, Contact his email id and be joyful in your life. (greatogudugu@gmail.com) Tel: +2348142250751 More gratitude and thanks to you again the Great Dr Ogudugu.

  29. What a wonderful spell caster. Very trustworthy, My husband cheated on me for Almost for two years. he ignore me for several months and left me with nothing, but i am happy today that Dr happy brought my husband back, I am so happy, Now my husband is all mine again. I can now say I’m happy again. Great spell from Dr happy, is genuine. I truly believe in him and his spells. he is a professional. I really enjoyed the result which i got, his love spell is marvelous, he is truly gifted, his love spell has brought me happiness, I am extremely pleased, it worked out to my test, he has the most powerful love spell, I recommend his love spell to anyone who is ready to get his or her lover back, contact happylovespell2@gmail.com or call him +2348133873774
    Crystal
    New Jersey USA

  30. i am Myers by name. Greetings to every one that is reading this testimony. I have been rejected by my husband after three(3) years of marriage just because another woman had a spell on him and he left me and the kid to suffer. one day when i was reading through the web, i saw a post on how this spell caster on this address salvationlovespell@gmail.com , have help a woman to get back her husband and i gave him a reply to his address and he told me that a woman had a spell on my husband and he told me that he will help me and after 2 days that i will have my husband back. i believed him and today i am glad to let you all know that this spell caster have the power to bring lovers back. because i am now happy with my husband. Thanks for Dr.paul . His email:salvationlovespell@gmail.com

  31. Wow i never thought i will be happy in my life ever again, i want you all to thank DR OTARU of OTARUSOLUTIONHOME@GMAIL.COM, he is a father that takes care of his children the spell caster of our time, he has saved me from a very ugly situation that almost made my life miserable and i want you all to thank him for me,my husband and i have be married for so many years now with children and the relationship was being threatened by a small girl in his working place,she was almost destroying my home i met so many spell casters but to no avail until i met a friend who came from africal and she told me about DR OTARU, and i decided to contact him and try him out as i was losing faith in all spell casters, but he told not to worry that now am in his temple everything will be alright he assured me 100% that his spell has no side effects and that it will work straight and save my home and my marriage and after he has performed the sacrifices and casting the spell, my husband came back to us with love and affection and he loved us more and more and he never looked back or none did his love for me waiver, if you are also experiencing this sort of your situation in your home, if your husband is drifting away, if you are experiencing a broken home or you have lost your husband to a young woman outside there then look no further help is here as OTARUSOLUTIONHOME@GMAIL.COM is ready to help you out okay for any of your problem is it financial needs, revenge spell, job spell, promotion spell what kind of spell do you need DR OTARU is going to solve it for you okay i have promised him to always talk of his good works to the world in general and to any body who cares to listen, you can email him on his personal email on OTARUSOLUTIIONHOME@GMAIL.COM and he will attend to you as soon as possible okay once again his email is OTARUSOLUTIONHOME@GMAIL.COM OR you can call him +2348107345943

  32. This is real take it serious, who will believe that a herb can cure herpes, i navel believe that this will work i have spend a lot when getting drugs from the hospital to keep me healthy, what i was waiting for is death because i was broke, one day i hard about this great man who is well know of HIV and cancer cure, i decided to email him, unknowingly to me that this will be the end of the herpes in my body, he prepare the herb for me, and give me instruction on how to take it, at the end of the one month, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me negative, i thought it was a joke, i went to other hospital was also negative, then i took my friend who was also herpes positive to the Dr abulu , after the treatment she was also confirm negative . He also have the herb to cure cancer. please i want every one with this virus to be free, that is why am dropping his email address, drabuluspelltemlpe@gmail.com do email him he is a great man. the government is also interested in this DR, thank you for saving my life, and I promise I will always testify for your good work.

  33. Frank davis

    DOCTOR OHIRI is indeed a great and powerful man. I am Frank Davis by name am from England. My girlfriend left me and didn’t want any contact with me, not even friendship. She said it was over between us and told me to move on with my life. She ignored my e-mails and refused to answer or return my phone calls. She called me an obsessed psychotic stalker and even threatened me with cops and restraining orders if I showed up. I was absolutely heartbroken and devastated. I thought my case was impossible to resolve until I found DOCTOR OHIRI on the internet. DOCTOR OHIRI casted a spell for me and my situation made a miraculous turn around like something out of a movie or fairy tale with a happy ending. I had a wonderful conversation with my girlfriend After 6 months of no contact, during which she offered out of the blue to come and spend time with me. My relationship has been consistently wonderful and stable. I still cant believe it, it is like a huge burden has been lifted from my shoulders. Thanks to the wonderful work of DOCTOR OHIRI. He knows his craft very well and deals on all kinds of spell. You can contact him via E-mail: Doctorohirispelltemple@hotmail.com, or you can whatsapp him on his mobile number: +2347069784152.

  34. I was heartbroken that my husband moved in with another woman so I had a spell to bring him back home and stop the affair he had with her. In just 2 days he left her and went to live at the hotel. He called to say so and get news of the kids. The discussion was pleasant, as if he was changing to become the man I knew when we got married. It was exactly as you said…. Now he’s back home and is absolutely crazy about me. I am so thrilled by this spell that I can’t find the right words to say how I feel right now. You are the best Dr UZOYA, All I can decently say is that you changed my life and saved the most important thing in my life: My Family.u can contact him on [driraborspellcaster@gmail.com] OR call him on +13019098775 Thanks

  35. My name is adu hope, I am from Canada, I have great joy in me as i am writing this testimony about the great man called Dr,UZOYA When my lover left me i never taught that i will be able to get him back after all he has put me through, But i am so happy that after the interference of Dr,UZOYA i was able to get my lover back after 48 hours and i can proudly say that who ever need help in getting there lover back should contact Dr,UZOYA on these contact details below driraborspellcaster@gmail.com for proper understanding of what i have just witness. And i promise that he will help you as he help me. call +13019098775

  36. kiberly Alice

    Hello,
    I am kiberly Alice I’m the most happiest person on the face of the earth, after 6 months of sadness and sorrow without being with the one i love, i tried all my possible best to make sure i make my lover happy but it never seems to work out well it was like am doing everything in vain but all thanks goes to Dr Okodu for coming to change all my worries and sadness to Joy. i knew the great man when i read some wonderful testimony about Dr Okodu how he has helped lots of people on their relationship problems i was reading a magazine when i saw great testimonies, as well my predicament then i decided not to waste time because i have missed my lover so much i decided to contact him and share all my problem with him which he told me not to worry that he is assuring me that within 48 hours everything would be sorted out i believed Dr Okodu so much because of how he has been helping many people, my boyfriend who left me for good suddenly replied my text and returned my calls and asked me to please forgive him i was so happy am so grateful to Dr Okodu for what he has done for me and i promise to testify his goodness all through my life. If you are there passing through the same problem or any kinds of problem contact this great man on his email address: okodujamesspellcaster@yahoo.com

    1. Getting your lover or husband back
    2. Money spell/ good luck spell
    3. Prosperity spell
    4. Protection spells
    5. Get a job spell
    6. Promotion spells
    7. Getting your money back
    8. Freedom spells
    9. Love spell
    10. Avenging spell

  37. Ann Wiggins

    “LOVE, Happiness, Trust, is the key to LIFE”. That was the word from Dr happy when I consulted his powerful Love Spell. I married the wrong man; I realized that after Three years of our unfruitful marriage. Everything was going from Best to Worst in our life, no child, I got demoted from work after our marriage, my husband was sacked a year after. His application for new job in various offices was constantly declined even though he was qualified enough. I was made to take care of my family with the low income I earn get that wasn’t enough to pay our rent. We keep praying a seeking for help from some people, my friends laugh at me behind because I was advised not to get married yet.It was one Thursday night that my husband woke me up and told me that has thought enough about our crisis, he said that our crisis is not ordinary and it’s beyond our spiritual level. He suggested we should consult Dr happy from testimonies he showed me online about how he has been helping families. I was afraid, I don’t like evil or spell but I supported him to contact him if he can help us. We consulted him via happylovespell2@gmail.com and he replied positively after 20munites with congratulating email that he can help us but he will need our pure heart and trusts in his work if he will cast the spell on us and purify our life. We agreed to his terms. He cast the spell and told us to expect results within 5days. I waited for three days nothing happened, so I started having doubt and blaming my husband for emailing Dr happy. It was on the fifth day that my husband was called for an interview and he got a well-paying work, I was prompted to a higher position. I missed my period on the 5th day and it was confirmed that I am with a baby. Things have really changed for us for good and we now have our own house and cars. I will never forget what Dr happy told us “LOVE is the key to LIFE”, this word keep me going. People that laughed at us are coming close for help and I am delighted to welcome them because my family is now blessed. Dr happy is a savior and man that keep to his word even when I doubted his powers at the end of the spell. Thank to your Oracle for helping us via happylovespell2@gmail.com

  38. i want to use this means to announce to the whole world the existence of strong power to cast any love spell by Dr OBIGBO. i have always doubted love spell because i have been scammed severally by fake spell casters. i almost lost hope until i met a friend who introduced me to Dr OBIGBO and gave me his number. i then called him and explained my relationship problems to him. he assured me that he will help me cast a love spell to get my Ex Lover back and that it will take two days and after which my Ex Lover shall return back to me on his knees. i decided to try him because the source of his contact was very legit. to my greatest surprise after all the long suffering, within 48 hours of contacting this man, my ex lover phill came back to me begging me and now we are happily married. i have promise to castigate his strong powers to the whole world so people who need his help can contact him for help. he is very strict and straight forward with his work and he does not delay work. you can contact him through the following means

    Email Address: OBIGBOLOVESPELLCASTER@OUTLOOK.com or call his mobile number:+2340852498003

  39. The spell caster others have been talking about called Dr. UZOYA that helped them get back their ex back, is real. I contacted him on Wednesday last week after my lover broke up with me because we could not bear children and I could not find a good job, As I am speaking now, Dr. UZOYA brought my lover back to my arms within 2 days. I have seen with my own eyes that Dr. UZOYA is real; he is real the right spell caster everyone need. Kindly contact him for any kind of help now I have a good Job and I just tested positive showing that I am pregnant. You need to contact Dr. UZOYA if you need any spiritual help via his private email address: [driraborspellcaster@gmail.com] u can also call him on +13019098775

  40. Thanks to dr LUKA who help me cure my DISEASE and he is capable of curing any kind of disease he is a powerful doctor .If you have a problem and you are looking for a real and genuine spell caster to solve that problem for you. Try Dr LUKA today, he might be the answer to your problems. Here’s is the contact:lukagozorspellhome@gmail.com Thank you once again……
    Contact him for the following:
    ACNE
    ZIKA VIRUS
    HIV
    ALS
    CANCER
    DIABETIS
    AHZEMER
    HERPES
    AND ANY KIND OF DISEASE

    (1)If you want your ex back.
    (2) if you always have bad dreams.
    (3)You want to be promoted in your office.
    (4)You want women/men to run after you.
    (5)If you want a child.
    (6)[You want to be rich.
    (7)You want to tie your husband/wife to be yours forever.
    (8)If you need financial assistance.
    (9)If you want to stop your Divorce.
    10)Help bringing people out of prison.
    (11)Marriage Spells
    (12)Miracle Spells
    (13)Beauty Spells
    (14)PROPHECY CHARM
    (15)Attraction Spells
    (16)Evil Eye Spells.
    (17)Kissing Spell
    (18)Remove Sickness Spells.
    (19)ELECTION WINNING SPELLS.
    (20)SUCCESS IN EXAMS SPELLS.
    (21) Charm to get who to love you.and lot more

    Contact now today on:lukagozorspellhome@gmail.com

  41. Amanda Mazzei

    My name is Amanda Mazzei From New York,I read some testimonies about a love spell caster on how he has helped lots of people in bringing back their ex lovers within 48 hours, Sincerely I was just thinking if that was real and if this man could really help bring back my lover whom I love so much. I decided to contact him because I love my partner very much and we have been apart for a couple of months I really missed him so much, I have tried all other means to get him back but couldn’t. I contacted: atilahealinghome@yahoo.com and he told me that my partner will come back to me in the next 12 hours,DR ATILA released him up to know how much i loved and wanted him back. And opened his eyes to picture how much we have share together.with the help of Dr ATILA we are happily back again.As I`m writing this testimony right now I`m the most happiest woman on earth and me and my partner are living a happy life and our love is now stronger than how it were even before our break up.All thanks goes to DR ATILA for the excessive work that he has done for me by helping me to get back with my partner. I would like to drop DR ATILA mail address and hope you see this testimony and contact him if you have a lover that you really want back so badly, His mail:(atilahealinghome@yahoo.com)or WHATS-APP NUMBER: +2347067607073.

  42. sandy sandra

    After being in relationship for 9 years,my husband broke up
    with me all was in
    vain, I wanted him back so much because of the love I have for him, I
    begged him with everything, I made promises but he refused. I
    explained my problem to someone online and she suggested that I should
    rather contact a spell caster that could help me cast a spell to bring
    him back but I am the type that never believed in spell, I had no
    choice than to try it, I emailed the spell caster, and he told me there
    was no problem that everything will be okay before seven days, that my
    ex will return to me before seven days, he cast the spell and
    surprisingly in the six day, it was around 4pm. My ex husband called me, I
    was so surprised, I answered the call and all he said was that he was
    so sorry for everything that happened, that he wanted me to return to
    him, that he loves me so much. I was so happy and went to him, that
    was how we started living together happily again. Since then, I have
    made promise that anybody I know that have a relationship problem, I
    would be of help to such person by referring him or her to the only
    real and powerful spell caster who helped me with my own problem and
    who is different from all the other once out there.So friends my advise is if you have such problem you can email him on (drowonaspelltemple@gmail.com) or you can whatsapp him with this number +2348115204568 Sir i am indeed grateful for the help, i will forever recommend my friends to you.

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