Archive for February, 2009

On Coffee Art

Thursday, February 26th, 2009

Hello there. I am afraid everything is Hotting Up ’round about now, so I won’t be able to post anything substantial here for a short while. However, I am going to the Darwin exhibition at the Natural History Museum in London this weekend, so I may have something interesting to say about that (other than just going all misty-eyed, sighing a deep sigh, and softly intoning “Darwin…”).

As a bit of filler, as the webcomicists say, I think I’ll show you something cool, but largely unrelated to the general subject matter of this blog.

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On GSK’s Announcement

Monday, February 16th, 2009

Hello again, reader; we have been seeing a lot of each other this week. This is my promised post on GSK’s recent announcement of a set of initiatives to help fight disease in the 50 poorest developing countries. I’ll go through some background about GSK’s business model and what has been happening to them recently, and then we’ll take a look through what the responses to the initiatives have been, and what my take on it is.
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On GSK’s Announcement - Prelude

Saturday, February 14th, 2009

Good evening, reader. As you may or may not have seen, all the newspapers today are reporting on the announcement by the drug company GlaxoSmithKline that they are starting a set of initiatives to help fight disease in the 50 poorest developing countries. Specifically, they have pledged to cap prices in these country at 25% of the UK price (which is cheep, but not as cheep as generic, non-branded drugs), to re-invest 20% of profits in these countries as aid and health care development, and to form a ‘patent pool’ to allow other companies and research bodies access to their patents for the development of drugs to aid the developing world (but this pool would not include HIV patents relating to HIV drugs, which is odd).

GSK has a bit of a tainted history, with a few things in their past to be ashamed of. For instance, they were one of the 39 pharmaceutical companies that attempted to sue South Africa top stop them importing genetic drugs, about which the CEO of GSK understatedly commented “I don’t think anybody can claim that was handled well”. They were also accused of covering up evidence that their antidepressant drug Paroxetine was addictive. They have recently been cutting down on research (as well as generally cutting jobs across the board); I’m not sure if that is related to their current proposals. Either way, I could imagine that clawing back a bit of good PR would be on the cards for GSK management. I also don’t rule out the possibility that Andrew Witty, who has only been CEO since May of last year, has a genuine desire to help the needy, and is willing to persuade his shareholders to take a hit in profits for the greater good.

I haven’t been able to find much out about this. The newspapers are reporting plenty, but I couldn’t find a GSK press release about it, and while Doctors Without Borders were called for comment some of the newspapers, their website doesn’t currently have anything on it. Likewise, I haven’t been able to find much in the way of reactions throughout the blogosphere yet. Thus, this post is just a brief prelude, without much in the way of analysis; I will try and get more information in the next few days, and put up a post with more on what is going on, and how it relates to the structure and function of the pharmaceutical industry in general.

On Darwin Day and the Cosmic Web

Thursday, February 12th, 2009

Good Morning, reader (if it is not morning, due to laziness or the inevitable passing of time, then Good Day). More importantly, Happy Darwin Day. Today is the 200th Anniversary of Darwin’s birth, and various events are taking place today and throughout this year, notably the Natural History Museum’s special exhibition. Nature has put on a special issue to mark the occasion, as well as a free podcast. I am also looking forward to the Endless Forms exhibition at the Fitzwilliam Museum here in Cambridge, about the connections between Darwin and visual art. And, as I know you love words as much as I, Ben Zimmer (brother to Carl Zimmer, one of my favourite science writers) has a blog post about Darwin’s influence of language.

On an unrelated note, my astrophysicist friend Olaf Davis, co-author of our game Biology or Physics (as featured on German TV!), has started up a blog. It is called Cosmic Web, and he intends to talk about astronomy and more general science communication. Olaf is a pretty awesome writer, and good at explaining complex ideas in simple ways, so the blog should we well worth checking out.

On Disease Association

Wednesday, February 11th, 2009

Hello again, my loyal blogventurer. The hectic nature of my life continues, though to my joy genomes are starting to fall into place (computationally, that is, not by insemination. Though doubtless that has also been going on. If not, god help us all). However, I think all this business is leading to general mental decline. Yesterday, in a fit of flustered Britishness, I thanked an ATM after using it, an event which, on retelling. triggering a ‘not-adapted-to-the-modern-world five’ from a quick-witted colleague.

Rambling introductory material aside, a few things have occured in the past week that have rekindled my passion for medical genetics. A few of us put together a talk on monoclonal antibodies (an awesome medical technology, which if you are lucky I may talk about in the future), and I signed up to work on disease gene association in the coming months. The latter I have a special affection for, an affection which I shall now point at you.
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